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Chemistry Colloquium Nov. 28, Dr. Jennifer A. Swift

Dr. Jennifer A. Swift

Georgetown University

Wednesday, November 28th 2012

11:00 AM – 12:00 PM

Science Complex Chemistry 121


“A Material Chemist’s View of Crystal Deposition Disease”

Presentation Abstract:  

Uric acid is a natural product in purine metabolism which can precipitate under physiologic conditions in a variety of solid state forms leading to symptoms associated with kidney stones and gout.  The evolution of these physiologic deposits is a multi-step process.  This talk will describe a variety of studies on three compounds – anhydrous uric acid (UA), uric acid dihydrate (UAD) and monosodium urate (MSU) – which are aimed at elucidated key factors important to the nucleation, growth and aggregation of these materials.  Analytical methods including optical microscopy, X-ray crystallography, and in situ atomic force microscopy (AFM) and their application to this problem will be described.  

About the Speaker:
Dr. Swift received her baccalaureate degree from Bowdoin College, a liberal arts college committed to undergraduate research, and her Ph.D. from Yale University. She has received a number of prestigious awards and currently serves as the NSF-REU program co-director at Georgetown.  Her research is highly interdisciplinary and covers different aspects of chemistry and materials science, including  x-ray crystallography, physical characterization methods, atomic force microscopy (AFM), organic synthesis, and/or computational modeling. 
For more information about Dr. Swift, please visit her webpage.